MYTIL-250 SOL

Description

MYTIL-250 is a broad-spectrum semi-synthetic bactericidal macrolide antibiotic synthesized from tylosin. It has an antibacterial spectrum that is predom-inantly effective against Mycoplasma, Pasteurella and Haemophilus spp. and various Gram-positive organisms such as Corynebacterium spp. It is believed to affect bacterial protein synthesis through binding to 50S ribosomal subunits. Cross-resistance between tilmicosin and other macrolide antibiot-ics has been observed. Following oral administration, tilmicosin is excreted mainly via the bile into the faeces, with a small proportion being excreted via the urine. with Tilmicosin-susceptible micro-organisms such as Mycoplasma spp. Pasteurella multocida, Actinobacil-lus pleuropneumoniae, Actinomyces pyogenes and Mannheimia haemolytica in calves, chickens, turkeys and swine.